MRI-based topographic parcellation of human neocortex: An anatomically specified method with estimate of reliability

MRI-based topographic parcellation of human neocortex: An anatomically specified method with estimate of reliability
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DOI:
10.1162/jocn.1996.8.6.566
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发表时间:
1996-11-01
影响因子:
3.2
通讯作者:
Kennedy, DN
Kennedy, DN
中科院分区:
医学3区
文献类型:
--
作者:
Caviness, VS;Meyer, J;Kennedy, DN

文献摘要

被引文献

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我们描述了一种基于磁共振图像的人类新大脑皮层分割系统,该系统保留了个体大脑的地形图独特性。根据这一系统,新皮质的细分完全基于一组特定的大脑地标的配置,主要是新皮质裂隙。这些都是存在的,但在每个人的大脑中它们的配置细节是独一无二的。我们在这里介绍了一种计算机辅助算法,它确保熟练的调查人员可以在可管理的时间段内执行分割例程。其次,我们概述了一组全面的约定,这些约定指定了如何通过解剖地标来定义分割单元的边界。观察者间对整体大脑皮层内分割单元的体素分配的平均一致性为80.2%。
We describe a system of parcellation of the human neocortex, based upon magnetic resonance images, that conserves the topographic uniqueness of the individual brain. Subdivision of the neocortex, according to this system, is based entirely upon the configuration of a specified set of cerebral landmarks, principally neocortical fissures. These are present but unique in the details of their configurations in each individual brain. We introduce here a computer-assisted algorithm that ensures that a skilled investigator can execute the parcellation routine in a manageable period of time. Secondly, we outline a comprehensive set of conventions that specify how the boundaries of parcellation units are defined by anatomic landmarks. The average interobserver agreement in voxel assignment to parcellation units within the overall neocortex nas 80.2%.