Motor-sensory recalibration leads to an illusory reversal of action and sensation
Motor-sensory recalibration leads to an illusory reversal of action and sensation
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DOI：
10.1016/j.neuron.2006.08.006
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发表时间：
2006-09-07
期刊：
影响因子：
16.2
通讯作者：
Eagleman, David M.
中科院分区：
文献类型：
--
作者：
Stetson, Chess;Xu Cui;Eagleman, David M.
为了判断因果关系，生物体必须确定其行为和感觉的时间顺序。然而，这种判断可能会被感觉通路的延迟变化所混淆，这表明需要动态的时间重新校准。为了测试这种机制，我们人为地在参与者的动作（按键）和随后的感觉（闪光）之间注入了固定的延迟。在参与者适应了这种延迟之后，在按键之后出现的意想不到的短延迟的闪光通常被认为是在按键之前发生的，这表明运动-感觉时间顺序判断的重新校准。当参与者经历幻觉逆转时，fMRI BOLD信号在前扣带皮层/内侧额叶皮层（ACC/MFC）增加，这是一个先前与冲突监测有关的大脑区域。这种错觉特异性的激活表明，大脑不仅保持了对时间的重新校准，而且还保持了一种较少可塑性的表征，以便与之进行比较。
To judge causality, organisms must determine the temporal order of their actions and sensations. However, this judgment may be confounded by changing delays in sensory pathways, suggesting the need for dynamic temporal recalibration. To test for such a mechanism, we artificially injected a fixed delay between participants' actions (keypresses) and subsequent sensations (flashes). After participants adapted to this delay, flashes at unexpectedly short delays after the keypress were often perceived as occurring before the keypress, demonstrating a recalibration of motor-sensory temporal order judgments. When participants experienced illusory reversals, fMRI BOLD signals increased in anterior cingulate cortex/medial frontal cortex (ACC/MFC), a brain region previously implicated in conflict monitoring. This illusion-specific activation suggests that the brain maintains not only a recalibrated representation of timing, but also a less-plastic representation against which to compare it.