Development of a clinical decision support system for antibiotic management in a hospital environment

Development of a clinical decision support system for antibiotic management in a hospital environment
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DOI:
10.1007/s13748-016-0089-x
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发表时间:
2016-08-01
影响因子:
4.2
通讯作者:
Palacios, Francisco
Palacios, Francisco
中科院分区:
其他
文献类型:
--
作者:
Canovas-Segura, Bernardo;Campos, Manuel;Palacios, Francisco

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由多重耐药细菌引起的感染上升已成为世界各地卫生机构面临的一个非常重要的问题,敦促他们更适当地使用抗生素。临床决策支持系统在这方面发挥着非常重要的作用。我们建议开发一个以医院实施的抗生素管理计划为重点的临床决策支持系统。对多用户视角的需要,包括反应性和主动性行为,以及许多不同的知识源的使用被确定为将这一临床情景与决策支持观点区分开来的主要要求。我们展示了产生式规则、本体、工作流建模和子组发现技术的组合可以用来满足这些需求。最后,我们描述了一个将在其上开发和测试这些技术的平台。
The rise of infections caused by multidrug-resistant bacteria has become a very important issue for health institutions around the world, urging them to a more appropriate use of antibiotics. Clinical decision support systems have a very important role in this area. We propose the development of a clinical decision support system focused on the antibiotic stewardship program implemented in hospitals. The need for a multi-user perspective, both reactive and proactive behaviours, and the use of many heterogeneous knowledge sources are identified as the main requirements that differentiate this clinical scenario from a decision support point of view. We show that a combination of production rules, ontologies, workflow modelling and subgroup discovery techniques could be used to fulfil these requirements. Finally, we describe a platform on which these techniques will be developed and tested.