Avoiding interpretational pitfalls in fluorescence imaging of the brain.
Avoiding interpretational pitfalls in fluorescence imaging of the brain.
复制标题
避免大脑荧光成像的解释陷阱。
DOI：
10.1038/s41583-022-00643-z
复制
发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Rusakov DA
中科院分区：
文献类型：
--
作者：
Rusakov DA
分子活动的荧光传感器彻底改变了我们对大脑的认识。然而，它们的信号报告了目标和传感器分子之间的反应，而不是感兴趣的活动本身。因此，了解传感器的位置、灵敏度和成像环境应有助于避免对其读数的误解。
Fluorescent sensors of molecular activity have revolutionized our knowledge of the brain. However, their signals report a reaction between the target and the sensor molecules rather than the activity of interest per se. Thus, understanding the location, sensitivity and imaging environment of a sensor should help to avoid misinterpretation of its readout.