A detector for a chronic implantable atrial tachyarrhythmia monitor

A detector for a chronic implantable atrial tachyarrhythmia monitor
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DOI:
10.1109/tbme.2007.903707
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发表时间:
2008-03-01
影响因子:
4.6
通讯作者:
Mehra, Rahul
Mehra, Rahul
中科院分区:
工程技术2区
文献类型:
--
作者:
Sarkar, Shantanu;Ritscher, David;Mehra, Rahul

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对房颤(AF)和心动过速(AT)的持续长期监测是临床上尚未满足的需要,可以通过长期植入的监护仪来满足。在准确监测参数的基础上改进治疗决策,例如每天的房颤/房颤负荷(小时/天)可能会导致临床结果的改善,如减少住院、症状和中风。本文介绍了一种既能检测房颤,又能检测室性心律失常的房颤/房颤检测器,以及一种用于室性反应更规则的房颤的辅助房颤检测器。使用了7个具有显著持续时间的房颤、房速和窦性心律的数据库来评估检测器的性能。所有有房颤记录的患者(N=124)均有房颤/房颤负荷,负荷检测的平均、中值和75%绝对误差分别为8.8分钟、0分钟和4分钟。在有房颤负荷(>=10分钟)的患者中,发现在96%的患者中,房颤/房颤检测器的负荷准确率在真实负荷的20%以内。特异度为94%,定义如下:在无房颤/房颤的患者记录(N=174)中,有房颤/房颤负荷的百分比
Continuous long-term monitoring of atrial fibrillation (AF) and tachycardia (AT) is an unmet clinical need, which could be met with a chronically-implanted monitor. Improved therapeutic decisions based on accurate monitoring of parameters, such as daily AF/AT burden (hours/day) may lead to improvements in clinical outcomes such as reduction in hospitalizations, symptoms, and strokes. This paper describes an AF/AT detector that detects AF as well as AT with an irregular ventricular response, and a supplementary AT detector for AT with more regular ventricular response. Seven databases with significant durations of AF, AT, and sinus rhythm were used to evaluate the performance of the detectors. All patient records with AF (N = 124) were detected by the AF/AT detector to have AF/AT burden with a mean, median, and 75 percentile of absolute error in burden detection of 8.8, 0, and 4 min, respectively. In patients having AF burden (>= 10 min), the AF/AT detector was found to have burden accuracy within 20% of true burden in 96% of patients. The specificity was 94%, defined as follows: in patient records without AF/AT (N = 174), the percentage with AF/AT burden