Syntheses of deuterated jasmonates for mass spectrometry and metabolism studies

Syntheses of deuterated jasmonates for mass spectrometry and metabolism studies
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DOI:
10.1002/jlcr.994
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发表时间:
2005-10-15
影响因子:
1.8
通讯作者:
Abrams, SR
Abrams, SR
中科院分区:
医学4区
文献类型:
--
作者:
Galka, PW;Ambrose, SJ;Abrams, SR

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Jasmonic acid and its metabolites play an essential role in the regulation of plant development and systemic defense responses. Isotopically labeled standards are required to quantify plant hormones for metabolism studies using mass spectrometry. A convenient method for the preparation of deuterated analogs of jasmonates is demonstrated. Modification of commercially available methyl jasmonate by base-catalyzed proton/deuterium exchange or Wittig reaction introduces either two or three heavy atoms into a molecule. Copyright (c) 2005 John Wiley & Sons, Ltd.