Full Adder and Full Subtractor Operations by DNA Self-Assembly
Full Adder and Full Subtractor Operations by DNA Self-Assembly
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DOI：
10.1166/asl.2011.1251
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发表时间：
2011-02
影响因子：
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通讯作者：
Yanfeng Wang;Junwei Sun;Guangzhao Cui;Xuncai Zhang
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文献类型：
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作者：
Yanfeng Wang;Junwei Sun;Guangzhao Cui;Xuncai Zhang
由于传统光刻制造技术中的光学波长限制和物理限制，基于硅的技术改进将很快开始接近其最终极限。自组装是解决接触问题最有前景的方法之一，成为分子电子学发展最重要的方向之一。在本文中，构建了三种稳定的DNA瓦片，包括x瓦片、y瓦片和初始化角c瓦片，以三个寡核苷酸作为输入和两个独立的荧光切割反应作为输出来执行全加器和全减器操作。这项工作表明，利用DNA自组装实现全加器和全减器是通过并行逻辑门运算来实现的。我们在这里讨论的方法是逻辑运算的基础，但似乎可以通过自组装使用分子计算机进一步扩展更复杂的逻辑电路。
Due to optical wavelength limitations in conventional lithographic fabrication techniques and physical limits, silicon-based technology improvements will soon begin to approach their ultimate limits. Self-assembly is one of the most prospective methods to overcome the contact problem, and became one of the most important directions of molecular electronics development. In this paper, three kinds of stable DNA tiles including the x tiles, y tiles and initialization corner c tiles are constructed to execute the full adder and full subtractor operations with three oligonucleotides as inputs and two independent fluorogenic cleavage reactions as outputs. This work indicates that the realization of the full adder and full subtractor using DNA self-assembly are carried with parallel logic gates operations. The method that we discuss here are fundamental to the logical operations, but it seems possible to further extend more complex logic circuits using a molecular computer by self-assembly.