Imaging of cholangiolocellular carcinoma of the liver
Imaging of cholangiolocellular carcinoma of the liver
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DOI：
10.1016/j.ejrad.2009.09.010
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发表时间：
2010-07-01
影响因子：
3.3
通讯作者：
Honda, Hiroshi
中科院分区：
文献类型：
--
作者：
Asayama, Yoshiki;Tajima, Tsuyoshi;Honda, Hiroshi
目的：胆管细胞癌（CoCC）目前被认为起源于肝祖细胞。本研究的目的是评估肝胆管细胞癌的影像学特征。材料和方法：5例手术切除的病例CoCC从4个机构进行了回顾性分析。5例患者均行动态CT增强扫描。3例行MRI检查，2例行肝动脉造影CT检查，3例行门脉动脉造影CT检查。结果：动态CT或MRI上2例表现为血供丰富的肿瘤伴延迟充盈，3例表现为周边强化伴向心性延迟充盈。CTAP显示肿瘤内门静脉持续存在或有微小的门脉血流斑点。结论：CoCC具有肝细胞癌和胆管细胞癌的双重影像学特征。无纤维包膜、无肿瘤坏死、位于肝脏外周、门静脉穿透肿瘤也是其特征性表现。(C)2009爱思唯尔爱尔兰有限公司保留所有权利。
Aim: Cholangiolocellular carcinoma (CoCC) is currently considered to originate from hepatic progenitor cells. The purpose of this study was to evaluate the imaging features of cholangiolocellular carcinoma of the liver.Materials and methods: Five cases of surgically resected cases of CoCC from 4 institutions were retrospectively evaluated. All of the five patients underwent contrast-enhanced dynamic CT. MRI and angio-CT including CT during arterioportography (CTAP) and CT during hepatic arteriography were performed in 3 and 2 patients, respectively. Histological evaluation was also performed and was correlated with radiographic findings.Results: On dynamic CT or MRI, the lesions presented hypervascular tumors with delayed washout in 2 cases and in the other 3 cases, the lesions showed peripheral enhancement with concentric delayed filling. On CTAP, the continued existence of portal veins or tiny spots of portal flow was identified in the tumors. Fibrous capsule or tumor necrosis was not observed.Conclusion: CoCC tumors have the dual imaging characteristics of hepatocellular carcinoma and cholangiocarcinoma. The absence of a fibrous capsule, the absence of tumor necrosis, peripheral location within the liver, and the presence of portal venous penetration within the tumor also appear to be characteristic features. (C) 2009 Elsevier Ireland Ltd. All rights reserved.