Diabetes in South-East Asia: An update

Diabetes in South-East Asia: An update
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DOI:
10.1016/j.diabres.2013.11.011
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发表时间:
2014-02-01
影响因子:
5.1
通讯作者:
Ma, Ronald Ching Wan
Ma, Ronald Ching Wan
中科院分区:
医学3区
文献类型:
--
作者:
Ramachandran, Ambady;Snehalatha, Chamukuttan;Ma, Ronald Ching Wan

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根据国际糖尿病联合会(IDF)的最新估计,东南亚(SEA)地区包括印度,斯里兰卡,孟加拉国,不丹,毛里求斯和马尔代夫,2013年有超过7200万成年糖尿病患者,预计到2035年将超过1.23亿。2型糖尿病(T2DM)是一种常见的糖尿病。虽然1型糖尿病(T1DM)在这些国家相对罕见,但其患病率也在上升。此外,大量(2430万)人还患有葡萄糖耐量受损(IGT)。当与他们的欧洲同行相比时,在这些人的临床和免疫表现中观察到几个特征性差异。在SEA地区,无论是在城市还是农村地区,T2DM的患病率都急剧增加,这主要与生活方式向城市化和工业化的转变有关。有证据表明,大部分T2DM可以通过改变生活方式来预防。然而,发病率和早期死亡率的发生是由于早期发现和治疗的医疗设施不足,以及糖尿病和相关疾病的管理不佳。这在很大程度上可以通过糖尿病的初级预防和提高公众和医疗保健提供者对疾病的认识来预防。迫切需要政府和非政府部门作出协调一致的努力,执行旨在预防、管理和监测这一疾病的国家方案。(C)2013爱思唯尔爱尔兰有限公司版权所有。
According to the recent estimates by the International Diabetes Federation (IDF), South East-Asia (SEA) Region consisting of India, Sri Lanka, Bangladesh, Bhutan, Mauritius and Maldives, is home to more than 72 million adults with diabetes in 2013 and is expected to exceed 123 million in 2035. Nearly 95% of people with diabetes have type 2 diabetes (T2DM). Although type 1 diabetes (T1DM) is relatively rare in these countries, its prevalence is also rising. Furthermore, a large number (24.3 million) of people also have impaired glucose tolerance (IGT). Several characteristic differences are seen in the clinical and immunological presentation of these people when compared with their European counterparts.A sharp increase in the prevalence of T2DM has been observed in the SEA Region, both in urban and rural areas, which is mostly associated with the lifestyle transitions towards urbanisation and industrialisation. Evidence suggests that a large portion of T2DM may be preventable by lifestyle modification. However, morbidity and early mortality occur as a result of inadequate healthcare facilities for early detection and initiation of therapy, as well as suboptimal management of diabetes and associated morbidities. This is largely preventable by primary prevention of diabetes and enhancing awareness about the disease among the public and the healthcare providers. There is an urgent need for concerted efforts by government and non-governmental sectors to implement national programmes aimed at prevention, management and surveillance of the disease. (C) 2013 Elsevier Ireland Ltd. All rights reserved.