Can we identify women at risk of pregnancy despite using emergency contraception? Data from randomized trials of ulipristal acetate and levonorgestrel
Can we identify women at risk of pregnancy despite using emergency contraception? Data from randomized trials of ulipristal acetate and levonorgestrel
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DOI：
10.1016/j.contraception.2011.02.009
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发表时间：
2011-10-01
期刊：
影响因子：
2.9
通讯作者：
Ulmann, Andre
中科院分区：
文献类型：
--
作者：
Glasier, Anna;Cameron, Sharon T.;Ulmann, Andre
背景：紧急避孕（EC）并不总是有效。临床医生应该意识到EC失败的潜在危险因素。研究设计：对两项随机对照试验的meta分析数据进行分析，比较醋酸乌普利司酮（UPA）和左炔诺孕酮的疗效，以确定与EC失败相关的因素。结果：肥胖女性的妊娠风险是正常体重指数女性的3倍以上(优势比（OR）， 3.60；95%置信区间（CI）， 1.96 ~ 6.53；p
Background: Emergency contraception (EC) does not always work. Clinicians should be aware of potential risk factors for EC failure.Study Design: Data from a meta-analysis of two randomized controlled trials comparing the efficacy of ulipristal acetate (UPA) with levonorgestrel were analyzed to identify factors associated with EC failure.Results: The risk of pregnancy was more than threefold greater for obese women compared with women with normal body mass index (odds ratio (OR), 3.60; 95% confidence interval (CI), 1.96-6.53; p