Usefulness of bile cytology in the diagnostic management of patients with biliary tract obstruction.
Usefulness of bile cytology in the diagnostic management of patients with biliary tract obstruction.
复制标题
胆汁细胞学在胆道梗阻患者诊断治疗中的作用。
作者：
Cobb Cj;Floyd Wn
：18名有胆道梗阻证据的患者，在两年的时间里，总共有29份令人满意的胆汁样本提交给诊断细胞学。我们对这29例标本进行了复习，以确定胆汁细胞学在梗阻性胆道疾病的诊断治疗中是否有用。21例胆汁标本来自恶性胆管狭窄患者，8例来自良性胆道梗阻患者。胆汁细胞学检查显示，8例恶性狭窄患者胆汁细胞学检查为癌阳性，2例恶性狭窄患者胆汁细胞学检查为恶性。没有假阳性。胆汁细胞学诊断特异度为100%，诊断灵敏度为48%，诊断准确率为62%。在仔细收集和及时处理后，胆汁被证明是细胞学评估的极好标本，并且是检测癌症引起胆道梗阻的其他诊断程序的有价值的辅助手段。
: Eighteen patients with evidence of biliary tract obstruction had a total of 29 satisfactory bile samples submitted for diagnostic cytology during a two-year period. These 29 specimens were reviewed in order to determine if bile cytology is useful in the diagnostic management of patients with obstructive biliary tract disease. Twenty-one of the bile specimens were from patients with malignant biliary stricture, and eight were from patients with benign biliary obstruction. Bile cytology was positive for carcinoma in eight samples from patients with malignant stricture and was inconclusive for malignancy in two. There were no false positives. The diagnostic specificity of bile cytology was 100%, the diagnostic sensitivity was 48%, and the diagnostic accuracy was 62%. When carefully collected and promptly processed, bile proved an excellent specimen for cytologic evaluation and was a valuable adjunct to other diagnostic procedures for the detection of carcinoma causing biliary tract obstruction.