Evaluation of fetal heart dimensions from 12 weeks to term
Evaluation of fetal heart dimensions from 12 weeks to term
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DOI：
10.1016/s0002-9149(00)01437-5
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发表时间：
2001-03-01
影响因子：
2.8
通讯作者：
Silverman, NH
中科院分区：
文献类型：
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作者：
Firpo, C;Hoffman, JIE;Silverman, NH
为了评估是否可以在孕中期进行胎儿心脏测量，我们使用最先进的超声设备检查了一组孕12至18周的正常妊娠。我们纵向检查了这一人口的间隔2周，以及在32周的妊娠。在四腔切面上，我们测量了心室和心房腔的尺寸，心室壁和室间隔的厚度，以及二尖瓣和三尖瓣的环尺寸。使用各种视图，我们还测量了心房、主动脉、肺动脉及其主要左、右分支、动脉导管、上级和下腔静脉的长径和横截面直径。为了测试测量值可能是模式的频率，我们将它们分为清晰且易于定义的测量值（统计学上良好）、不清楚的测量值（统计学上不好）或根本没有测量的测量值（无）。然后通过回归分析、方差分析和协方差分析对数据进行分析。可靠测量的频率与胎龄成反比。测量的拐点大约在16周。本纵向研究的数据与我们先前研究的数据进行了比较。由于这些研究之间的测量结果没有发现统计学差异，因此将数据合并到一个大组中，并计算所有变量的平均值和SEE。我们的研究表明，目前的经腹成像，胎儿心脏测量可以可靠地在正常胎儿从16周的妊娠。在年轻的正常胎儿中获得数据的频率表明在异常胎儿中不太可能常规地进行可靠的观察
To evaluate whether fetal cardiac measurements can be made in the second trimester, we examined a cohort of normal pregnancies between 12 and 18 weeks' gestation using state-of-the-art ultrasound equipment. We examined this population longitudinally at intervals of 2 weeks, as well as at 32 weeks' gestation. From the 4-chamber view we measured the ventricular and atrial cavity dimensions, the thickness of the ventricular walls and septum at end-diastole, and the annulus dimensions of the mitral and tricuspid valves. Using a variety of views we also measured the long and cross-sectional diameters of the atria, the aorta, the pulmonary artery and its main left and right branches, the ductus arteriosus, and the superior and inferior veno cavae. To test the frequency with which measurements could be mode, we divided them into measurements that were clear and easy to define (statistically good), to those that were unclear (statistically bad), or those that were not measured at all (none). Data were then analyzed by regression analysis, analysis of variance, and covariance. The frequency of reliable measurements varied inversely with gestational age. The inflection point for measurements was approximately at 16 weeks. Data from this longitudinal study were evaluated agoinst those obtained from our previous study. Because no statistical differences were found in measurements between these studies where they overlapped, the data were pooled into 1 large group and the mean and SEEs calculated for all variables. Our study demonstrates that with current transabdominal imaging, fetal cardiac measurements can be made reliably in normal fetuses from 16 weeks' gestation onward. The frequency of obtaining data in younger normal fetuses suggests it is unlikely that reliable observations can be made routinely in abnormal fetuses