Heteroatom substitution for the development of near-IR lumiphores

Heteroatom substitution for the development of near-IR lumiphores
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DOI:
10.1016/j.trechm.2022.11.004
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发表时间:
2022-12
影响因子:
15.7
通讯作者:
Remi S. Dado;Lauren E McNamara;Mya Powers-Nash;John S. Anderson
Remi S. Dado;Lauren E McNamara;Mya Powers-Nash;John S. Anderson
中科院分区:
化学1区
文献类型:
--
作者:
Remi S. Dado;Lauren E McNamara;Mya Powers-Nash;John S. Anderson

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近红外 (NIR) 荧光体对于生物应用非常有利,因为它们的发射落在组织透明区域内。然而,这些染料由于其低跃迁能而导致量子产率低。杂原子取代最近已成功用于使各种染料支架中的发射发生红移,同时保持明亮的发射。
Near-IR (NIR) lumiphores are advantageous for biological applications as their emission falls within the tissue-transparent region. However, these dyes suffer from low quantum yields as a consequence of their low transition energy. Heteroatom substitution has recently been successfully used to bathochromically shift emission in various dye scaffolds while maintaining bright emission.