Apatite formation on surface titanate layer with different Na content on Ti metal
Apatite formation on surface titanate layer with different Na content on Ti metal
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DOI：
10.2109/jcersj2.118.19
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发表时间：
2010-01-01
影响因子：
1.1
通讯作者：
Kokubo, Tadashi
中科院分区：
文献类型：
--
作者：
Kawai, Takahiro;Kizuki, Takashi;Kokubo, Tadashi
早期发现，当钛金属经过NaOH和热处理在其表面形成钛酸钠时，通过在活体表面形成的磷灰石层自发地与活体骨结合。这种具有生物活性的钛金属应用于人工髋关节，在日本已投入临床使用。在对髋关节制造工艺的研究中发现，NaOH处理后的Ti金属表层钠含量随洗涤条件变化较大，且NaOH和热处理后的Ti金属长期在潮湿环境中磷灰石形成能力容易下降。在本研究中，NaOH处理后通过水或HCl处理系统地改变了Ti金属表面层的钠含量。研究了表面层的钠含量对NaOH和热处理的Ti金属在模拟体液中磷灰石形成能力及其在潮湿环境中的稳定性的影响。结果发现，当NaOH处理后用水处理Ti金属以除去表面层中的部分钠离子并进行热处理时，经NaOH和热处理的Ti金属提供高且稳定的磷灰石形成能力。 (C)2010 日本陶瓷学会。版权所有。
It was early shown that Ti metal spontaneously bonds to living bone through,in apatite layer formed on its surface in the living body, when it was subjected to NaOH and heat treatment to form a sodium titanate on its surface. This kind of bioactive Ti metal was applied to artificial hip joint and already clinically used in Japan. During the study of fabrication process of the hip joint, it was found that sodium content of the surface layer of the Ti metal is largely varied with washing condition after the NaOH treatment, and that apatite-forming ability of the NaOH- and heat-treated Ti metal is liable to decrease in humid environment for a long period. In the present study, the sodium content of the surface layer of the Ti metal was systematically changed by water or HCl treatment after NaOH treatment. Effect of the sodium content of the surface layer on apatite-forming ability in a simulated body fluid and its stability in humid environment of the NaOH- and heat-treated Ti metal were investigated. As a result, it was found that the NaOH- and heat-treated Ti metal gives high and stable apatite-forming ability, when the Ti metal was treated with water after the NaOH treatment to remove partially sodium ions in the surface layer, and subjected to heat treatment. (C)2010 The Ceramic Society of Japan. All rights reserved.