Primary Immunodeficiency Classification on Smartphone
Primary Immunodeficiency Classification on Smartphone
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DOI：
10.1007/s10875-016-0354-6
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发表时间：
2017-01-01
影响因子：
9.1
通讯作者：
Aziz Bousfiha, Ahmed
中科院分区：
文献类型：
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作者：
Jeddane, Leila;Ouair, Hind;Aziz Bousfiha, Ahmed
原发性免疫缺陷包括至少300种遗传定义的单基因先天性免疫缺陷，表现为从感染易感性到自身免疫和炎症的广泛表现。国际免疫学会联合会（IUIS）原发性免疫缺陷专家委员会每隔一年举行一次会议，更新人类原发性免疫缺陷（PID）的分类。近年来，IUIS PID专家委员会已经发布了两种形式的分类：已知PID的完整目录，分为九个表，共享给定的发病机制，以及基于表型和实验室结果的更用户友好的分类[1，2]。
Primary immunodeficiencies comprise at least 300 genetically defined single-gene inborn errors of immunity, presenting a broad spectrum of manifestations from susceptibility to infections to autoimmunity and inflammation. The International Union of Immunological Societies (IUIS) Expert Committee on Primary Immunodeficiency meets every other year to update the classification of human primary immunodeficiencies (PIDs). In recent years, two forms of classification have been published by the IUIS PID expert committee: a complete catalog of known PIDs subdivised in nine tables sharing a given pathogenesis, and a more userfriendly classification based on phenotype and laboratory results [1, 2].