MEMORY-RELATED PROCESSING OF COMPLEX SOUND PATTERNS IN HUMAN AUDITORY-CORTEX - A MEG STUDY
MEMORY-RELATED PROCESSING OF COMPLEX SOUND PATTERNS IN HUMAN AUDITORY-CORTEX - A MEG STUDY
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DOI：
10.1097/00001756-199304000-00012
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发表时间：
1993-04-01
期刊：
影响因子：
1.7
通讯作者：
NAATANEN, R
中科院分区：
文献类型：
--
作者：
ALHO, K;HUOTILAINEN, M;NAATANEN, R
使用24通道磁力计记录了人脑对复杂声音模式的反应。声音模式由9个连续的50 ms片段组成，每个片段具有不同的频率。其中一个节段的频率的罕见变化引起磁失配响应（MMNm），其在异常节段发作后约200 ms达到峰值，并且类似于电失配负性（MMN）。最能解释MMNM的等效电流偶极子位于颞上听觉皮层，这表明声音模式的记忆痕迹储存在该区域。
RESPONSES of the human brain to a complex sound pattern were recorded with a 24 channel magnetometer. The sound pattern consisted of 9 successive 50 ms segments, each with a different frequency. An infrequent change in the frequency of one of the segments elicited a magnetic mismatch response (MMNm) which peaked at about 200 ms after the deviant segment onset and resembled the electrical mismatch negativity (MMN). The equivalent current dipole which best explained the MMNM was located in the supratemporal auditory cortex, suggesting that a memory trace for the sound pattern was stored in that region.