Viral hepatitis complicating the Dubin-Johnson syndrome.
Viral hepatitis complicating the Dubin-Johnson syndrome.
复制标题
病毒性肝炎并发杜宾-约翰逊综合征。
DOI：
10.1016/s0016-5085(19)33321-9
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发表时间：
1972
期刊：
影响因子：
29.4
通讯作者：
B. Combes
中科院分区：
文献类型：
--
作者：
A. Ware;E. Eigenbrodt;J. Shorey;B. Combes
一名患有Dubin-Johnson综合征的年轻黑人妇女患上了急性澳大利亚抗原阳性病毒性肝炎。组织学研究证实了先前描述的Dubin-Johnson色素在肝炎恢复期从她的肝脏中消失。此时，长期溴磺酞研究证明了有机阴离子的肝脏排泄缺陷的持续性。这证实了Dubin-Johnson综合征患者肝脏中的色素是排泄缺陷的结果而不是其原因的假设。
A young black woman with the Dubin-Johnson syndrome developed acute Australia antigen-positive viral hepatitis. Histological studies have reaffirmed the previously described disappearance of the Dubin-Johnson pigment from her liver in the convalescent phase of the hepatitis. Prolonged Bromsulphalein studies at this time have demonstrated the persistence of the hepatic excretory defect for organic anions. This confirms the supposition that the pigment in the livers of patients with the Dubin-Johnson syndrome is the result of the excretory defect rather than its cause.