MULTICOMPONENT REACTIONS IN ORGANIC-CHEMISTRY
MULTICOMPONENT REACTIONS IN ORGANIC-CHEMISTRY
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DOI：
10.1016/s0160-9327(05)80086-9
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发表时间：
1994-01-01
期刊：
影响因子：
0.6
通讯作者：
HORL, W
中科院分区：
文献类型：
--
作者：
UGI, I;DOMLING, A;HORL, W
传统上，有机合成是通过两种组分之间的一系列反应来实现的：这样做的一个后果是最终产率可能非常低。然而，人们早就知道，有效的合成可以同时使用三种或有时更多的反应物进行，并且工业上使用了一些这样的方法。近年来，人们利用先进的计算机技术系统地研究了这类过程，并成功地使用多达七种组分进行了合成。
Traditionally, organic syntheses are effected by a sequence of reactions between two components: one consequence of this is that final yields can be very low. It has long been known, however, that effective syntheses can be carried out using three, or sometimes more, reactants simultaneously and a few such processes are used industrially. In recent years processes of this kind have been systematically investigated using sophisticated computer techniques, and successful syntheses have been achieved using as many as seven components.