Human chemosignals of disgust facilitate food judgment.
Human chemosignals of disgust facilitate food judgment.
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DOI：
10.1038/s41598-018-35132-w
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发表时间：
2018-11-19
影响因子：
4.6
通讯作者：
Li W
中科院分区：
文献类型：
--
作者：
Zheng Y;You Y;Farias AR;Simon J;Semin GR;Smeets MA;Li W
选择食物并不是人们每天需要做出的微不足道的决定，它往往会受到社会的影响。在这里，我们研究了通过身体分泌物的化学信号在啮齿动物和其他动物中观察到的食物偏好社会传播（STFP）的人类同源物。一组捐赠者在厌恶或中性状态下产生的人类社会化学信号（汗液）被呈现给在功能磁共振成像（fMRI）过程中接受两种替代强制选择食物健康判断任务的参与者。反应速度和两个关键信号检测指数——d'（歧视敏感性）和β（反应偏差）——一致表明，厌恶的社会化学信号促进了食品健康决策，而主要厌恶诱发因素（厌恶气味）则损害了判断。功能磁共振成像分析（厌恶与中性汗水）显示，梭形面部区域（FFA）、杏仁核和眶额皮质（OFC）在食物判断过程中参与处理厌恶的社会化学信号。重要的是，跨模式（嗅觉与视觉面部表情）的社会信号的双重对比表明，FFA 和 OFC 对厌恶的社会化学信号表现出优先反应。总之，我们的研究结果为人类 STFP 提供了初步证据，即通过参与大脑的社交和情感区域，将社会化学信号纳入食物决策。
Choosing food is not a trivial decision that people need to make daily, which is often subject to social influences. Here, we studied a human homolog of social transmission of food preference (STFP) as observed in rodents and other animals via chemosignals of body secretions. Human social chemosignals (sweat) produced during a disgust or neutral state among a group of donors were presented to participants undergoing a 2-alternative-forced-choice food healthiness judgment task during functional magnetic resonance imaging (fMRI). Response speed and two key signal detection indices—d’ (discrimination sensitivity) and β (response bias)—converged to indicate that social chemosignals of disgust facilitated food healthiness decisions, in contrast to primary disgust elicitors (disgust odors) that impaired the judgment. fMRI analyses (disgust vs. neutral sweat) revealed that the fusiform face area (FFA), amygdala, and orbitofrontal cortex (OFC) were engaged in processing social chemosignals of disgust during food judgment. Importantly, a double contrast of social signaling across modalities (olfactory vs. visual—facial expressions) indicated that the FFA and OFC exhibited preferential response to social chemosignals of disgust. Together, our findings provide initial evidence for human STFP, where social chemosignals are incorporated into food decisions by engaging social and emotional areas of the brain.
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社会大脑：社会知识的神经基础。
影响因子：
24.8
作者：
Adolphs, Ralph
通讯作者：
Adolphs, Ralph
影响因子：
8.2
作者：
de Groot, Jasper H. B.;Smeets, Monique A. M.;Semin, Gun R.
通讯作者：
Semin, Gun R.
影响因子：
4.1
作者：
de Groot, Jasper H. B.;Semin, Gun R.;Smeets, Monique A. M.
通讯作者：
Smeets, Monique A. M.
影响因子：
8.2
作者：
de Groot, Jasper H. B.;Smeets, Monique A. M.;Semin, Gun R.
通讯作者：
Semin, Gun R.
DOI：
10.1126/science.1249168
发表时间：
2014-03-21
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Bushdid C;Magnasco MO;Vosshall LB;Keller A
通讯作者：
Keller A