Impact of smoking reduction on coronary heart disease mortality trends during 1981-2000 in England and Wales.
Impact of smoking reduction on coronary heart disease mortality trends during 1981-2000 in England and Wales.
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DOI：
10.1186/1617-9625-1-3-185
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发表时间：
2003-09-15
影响因子：
3.7
通讯作者：
Capewell S
中科院分区：
文献类型：
--
作者：
Unal B;Critchley J;Capewell S
探讨英格兰和威尔士冠心病（CHD）死亡率下降的多少可归因于吸烟率的变化。先前验证的基于细胞的IMPACT冠心病死亡率模型用于估计1981年至2000年间英格兰和威尔士人口吸烟率变化预防或推迟的死亡。从常规数据来源获得冠心病死亡率统计数据和吸烟人群趋势。1981年至2000年间，英格兰和威尔士25-84岁成年人的吸烟率在男性中从43%下降到28%，在女性中从35%下降到24%。在男性中，大多数下降发生在55岁以上的人群中。老年妇女的吸烟率变化不大。估计有29,460人因人口吸烟率下降而避免或推迟死亡。这种益处主要体现在男性身上（86%的dpp和14%的女性）。与1981年相比，2000年英格兰和威尔士吸烟流行率的大幅下降导致冠心病死亡人数减少了29460人。这就强调了制定国家战略并制定全面烟草控制规划以进一步减少吸烟的重要性。
To explore how much of the coronary heart disease (CHD) mortality fall in England and Wales can be attributed to changes in smoking prevalence. A previously validated cell-based IMPACT CHD mortality model was used to estimate the deaths prevented or postponed by changes in population smoking prevalence in England and Wales between 1981 and 2000. CHD mortality statistics and population trends in smoking were obtained from routine data sources. In England and Wales between 1981 and 2000, smoking prevalence in adults aged 25–84 decreased from 43% to 28% in men and from 35% to 24% in women. In men, most of the decrease occurred in those aged over 55. Smoking prevalence changed little in older women. An estimated 29,460 deaths were prevented or postponed (DPP) by this population reduction in smoking prevalence. Most of this benefit was seen in men (86% of the DPPs versus 14% in women). Large declines in smoking prevalence accounted for 29,460 fewer CHD deaths in England and Wales in 2000 compared with 1981. This emphasises the importance of a national strategy with comprehensive tobacco control programmes to further reduce smoking.