Acetylcholine increases the level of diglyceride in mouse pancreas.
Acetylcholine increases the level of diglyceride in mouse pancreas.
复制标题
乙酰胆碱会增加小鼠胰腺中甘油二酯的水平。
DOI:
10.1016/s0006-291x(74)80476-6
复制
发表时间:
1974
影响因子:
3.1
通讯作者:
M. Hokin
中科院分区:
文献类型:
--
作者:
M. Banschbach;R. Geison;M. Hokin
Incubation of mouse pancreas with 10−5M or 10−4M acetylcholine (plus eserine) resulted in increased tissue diglyceride levels. Diglyceride rose from 0.5 μmoles per gram fresh tissue in unstimulated pancreas to 1.2 and 3.6 μmoles, respectively, in acetylcholine-stimulated tissue. The linear increase in diglyceride level with time at 10−4M acetylcholine was blocked and reversed by 10−5M atropine. When atropine was added, the level of diglyceride fell to the control, unstimulated value. The increase in diglyceride level was greater than could be accounted for by hydrolysis of phosphatidylinositol or phosphatidic acid.