Bovine tuberculosis infection in wild mammals in the South-West region of England: A survey of prevalence and a semi-quantitative assessment of the relative risks to cattle
Bovine tuberculosis infection in wild mammals in the South-West region of England: A survey of prevalence and a semi-quantitative assessment of the relative risks to cattle
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DOI：
10.1016/j.tvjl.2005.11.011
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发表时间：
2007-03-01
影响因子：
2.2
通讯作者：
Cheeseman, C. L.
中科院分区：
文献类型：
--
作者：
Delahay, R. J.;Smith, G. C.;Cheeseman, C. L.
在英国，獾与牛分枝杆菌向牛的传播有关，但关于其他野生哺乳动物的潜在作用的信息很少。本文介绍了英国最大的M.其他野生哺乳动物中的牛感染。对来自英格兰西南地区的哺乳动物尸体（4715）进行了系统的尸检、组织微生物培养和分离株spoligotyping。在狐狸、白鼬、臭鼬、普通鼩、黄颈鼠、林鼠、田鼠、灰松鼠、狍、红鹿、梅花鹿和赤麂中均发现了感染。鹿的流行率可能被低估了，因为大多数鹿是不完整的尸体，这降低了检测感染的可能性。在威尔特郡、萨默塞特、德文郡和康沃尔郡、格洛斯特郡和赫里福德郡发现了感染病例。病变被发现在一个高比例的spoligotype阳性休闲，红色和狍，和一个单一的狐狸，白鼬和山羌。M.牛的spoligotypes发生在类似的频率发生在牛和獾。关于野生哺乳动物的流行率、病理学、丰度和生态学的数据被纳入相对于獾的牛传播可能性的半定量风险评估。虽然大多数物种呈现出相对较低的风险，但与赤麂、鱼子、赤鹿，特别是休闲鹿相关的较高值和不确定性表明，它们需要进一步调查。结果表明，鹿应该被认为是潜在的，虽然可能是局部的，牛的感染源。皇冠版权所有（c）2005年出版的爱思唯尔有限公司保留所有权利。
In the United Kingdom, badgers are implicated in the transmission of Mycobacterium bovis to cattle, but little information is available on the potential role of other wild mammals. This paper presents the results of the largest systematic UK survey of M. bovis infection in other wild mammals. Mammal carcasses (4715) from throughout the South-West region of England were subjected to a systematic post mortem examination, microbiological culture of tissues and spoligotyping of isolates. Infection was confirmed in fox, stoat, polecat, common shrew, yellow-necked mouse, wood mouse, field vole, grey squirrel, roe deer, red deer, fallow deer and muntjac. Prevalence in deer may have been underestimated because the majority were incomplete carcasses, which reduced the likelihood of detecting infection. Infected cases were found in Wiltshire, Somerset, Devon and Cornwall, Gloucestershire and Herefordshire. Lesions were found in a high proportion of spoligotype-positive fallow, red and roe deer, and a single fox, stoat and muntjac. M. bovis spoligotypes occurred in a similar frequency of occurrence to that in cattle and badgers. Data on prevalence, pathology, abundance and ecology of wild mammals was integrated in a semi-quantitative risk assessment of the likelihood of transmission to cattle relative to badgers. Although most species presented a relatively low risk, higher values and uncertainty associated with muntjac, roe, red and in particular fallow deer, suggest they require further investigation. The results suggest that deer should be considered as potential, although probably localised, sources of infection for cattle. Crown Copyright (c) 2005 Published by Elsevier Ltd. All rights reserved.