Association of Resistance Exercise, Independent of and Combined With Aerobic Exercise, With the Incidence of Metabolic Syndrome
Association of Resistance Exercise, Independent of and Combined With Aerobic Exercise, With the Incidence of Metabolic Syndrome
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DOI：
10.1016/j.mayocp.2017.02.018
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发表时间：
2017-08-01
影响因子：
8.9
通讯作者：
Blair, Steven N.
中科院分区：
文献类型：
--
作者：
Bakker, Esmee A.;Lee, Duck-chul;Blair, Steven N.
目的：确定独立于有氧运动或与有氧运动相结合的抗阻运动与发生代谢综合征 (MetS) 的风险之间的关系。 患者和方法：研究队列包括 1987 年 1 月 1 日至 2006 年 12 月 31 日期间在德克萨斯州达拉斯库珀诊所接受全面体检的成年人（平均 +/- SD 年龄，46 +/- 9.5 岁）。通过自我报告的频率和每周分钟数评估运动情况阻力和有氧运动，并在基线时满足美国身体活动指南（阻力运动 >= 2 天/周；有氧运动 >= 500 代谢当量分钟/周）。 MetS 的发生率基于国家胆固醇教育计划成人治疗小组 III 标准。我们使用 Cox 回归来生成风险比 (HR) 和 95% CI。结果：在 7418 名参与者中，1147 名 (15%) 人在中位随访 4 年（最长 19 年；最短 0.1 年）期间出现 MetS。在调整潜在的混杂因素和有氧运动后，符合抗阻运动指南与 MetS 风险降低 17% 相关（HR，0.83；95% CI，0.73-0.96；P=.009）。此外，与无抗阻运动相比，每周少于 1 小时的抗阻运动与 MetS 发生风险降低 29% 相关（HR，0.71；95% CI，0.56-0.89；P=.003）。然而，大量的阻力运动并没有带来更多的好处。同时满足推荐的阻力运动和有氧运动指南的个体发生 MetS 的风险降低 25%（HR，0.75；95% CI，0.63-0.89；P
Objective: To determine the association of resistance exercise, independent of and combined with aerobic exercise, with the risk of development of metabolic syndrome (MetS).Patients and Methods: The study cohort included adults (mean +/- SD age, 46 +/- 9.5 years) who received comprehensive medical examinations at the Cooper Clinic in Dallas, Texas, between January 1, 1987, and December, 31, 2006. Exercise was assessed by self-reported frequency and minutes per week of resistance and aerobic exercise and meeting the US Physical Activity Guidelines (resistance exercise >= 2 d/wk; aerobic exercise >= 500 metabolic equivalent min/wk) at baseline. The incidence of MetS was based on the National Cholesterol Education Program Adult Treatment Panel III criteria. We used Cox regression to generate hazard ratios (HRs) and 95% CIs.Results: Among 7418 participants, 1147 (15%) had development of MetS during a median follow-up of 4 years (maximum, 19 years; minimum, 0.1 year). Meeting the resistance exercise guidelines was associated with a 17% lower risk of MetS (HR, 0.83; 95% CI, 0.73- 0.96; P=.009) after adjusting for potential confounders and aerobic exercise. Further, less than 1 hour of weekly resistance exercise was associated with 29% lower risk of development of MetS (HR, 0.71; 95% CI, 0.56-0.89; P=.003) compared with no resistance exercise. However, larger amounts of resistance exercise did not provide further benefits. Individuals meeting both recommended resistance and aerobic exercise guidelines had a 25% lower risk of development of MetS (HR, 0.75; 95% CI, 0.63-0.89; P