Preventive effect of a chicken extract on the development of hypertension in stroke-prone spontaneously hypertensive rats
Preventive effect of a chicken extract on the development of hypertension in stroke-prone spontaneously hypertensive rats
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DOI：
10.1271/bbb.66.1108
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发表时间：
2002-05-01
影响因子：
1.6
通讯作者：
Tanaka, T
中科院分区：
文献类型：
--
作者：
Matsumura, Y;Kita, S;Tanaka, T
以易卒中的自发性高血压大鼠(SHRSP)为动物模型，研究了传统保健食品鸡肉提取物(BEC)的降压作用。动物从6周龄到25周龄，饮用含或不含BEC的水。与对照组相比，饲喂BEC组大鼠患高血压的几率显著降低。BEC组大鼠血尿素氮和血肌酐水平明显低于对照组，提示BEC对肾小球功能有改善作用。因此，BEC似乎可以作为预防高血压和肾脏损伤的一种有效方法。
The antihypertensive effect of Brand's Essence of Chicken (BEC), a popular chicken extract used as a traditional health food, was examined with strokeprone spontaneously hypertensive rats (SHRSPs). The animals were maintained from 6 to 25 weeks of age on drinking water with or without BEC. The BEC-fed group showed a significant reduction in the development of hypertension when compared with the control animals. The levels of blood urea nitrogen and plasma creatinine in the BEC-fed group were significantly lower than those in the control group, suggesting that the renal glomerular function had been improved by the daily administration of BEC. It thus seems likely that BEC would be useful as a prophylactic treatment against the development of hypertension and renal injury.