Toward a Synthetic Access to Jatropha-5,12-dienes by Ring-Closing Metathesis: Detours and Dead-Ends
Toward a Synthetic Access to Jatropha-5,12-dienes by Ring-Closing Metathesis: Detours and Dead-Ends
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DOI：
10.1055/s-0034-1380192
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发表时间：
2015-07-01
影响因子：
2.6
通讯作者：
Hiersemann, Martin
中科院分区：
文献类型：
--
作者：
Butt, Lena;Schnabel, Christoph;Hiersemann, Martin
从旨在多羟基化的麻风树-5，12-二烯的合成的努力的结果公布。追求由连续的羟醛加成和闭环复分解组成的明显预先合格的图，以构建天然存在的类麻黄素的完全氧化的反式双环[10.3.0]十五烷支架。
Results from efforts aimed at the synthesis of polyhydroxylated jatropha-5,12-dienes are unveiled. An apparently pre-qualified plot consisting of successive aldol addition and ring-closing metathesis was pursued in order to construct the fully oxidized trans-bicyclo[10.3.0]pentadecane scaffold of naturally occurring jatrophanoids.