THE PREVALENCE AND INCIDENCE OF SYSTEMIC LUPUS-ERYTHEMATOSUS IN BIRMINGHAM, ENGLAND - RELATIONSHIP TO ETHNICITY AND COUNTRY OF BIRTH
THE PREVALENCE AND INCIDENCE OF SYSTEMIC LUPUS-ERYTHEMATOSUS IN BIRMINGHAM, ENGLAND - RELATIONSHIP TO ETHNICITY AND COUNTRY OF BIRTH
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DOI：
10.1002/art.1780380415
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发表时间：
1995-04-01
影响因子：
--
通讯作者：
BACON, PA
中科院分区：
文献类型：
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作者：
JOHNSON, AE;GORDON, C;BACON, PA
目的：确定英国伯明翰市1992年1月1日系统性红斑狼疮（SLE）的时点患病率和1991年SLE的发病率。方法：采用6种资料来源确定确诊SLE患者，包括主治医生和初级保健医生的通知、狼疮患者支持小组、医院住院和实验室数据。结果：242例SLE患者中，（227名女性，15名男性）：发病率27.7/100 000（95%置信区间为24.2-31.2/100，000），非洲裔加勒比女性为206.0/100，000。1991年，33例患者发生SLE：发病率为3.8/100，000/year（95%置信区间为2.5-5.1/100，000/year）。结论：本研究说明了英国发病率和患病率的巨大差异，取决于种族群体和出生地。
Objective, To establish the point prevalence of systemic lupus erythematosus (SLE) on January 1, 1992, and the incidence of SLE during 1991, in Birmingham, England, a large city with a broad ethnic mix,Methods, Six sources were used to ascertain patients with diagnosed SLE, including notification by attending and primary care physicians, the lupus patient support group, and hospital inpatient and laboratory data,Results, There were 242 SLE patients (227 females, 15 males) identified: prevalence rate 27.7/100,000 (95% confidence interval 24.2-31.2/100,000) in the population and 206.0/100,000 in Afro-Caribbean females, No significant differences in female ethnic prevalence rates by place of birth were observed, Thirty-three patients developed SLE in 1991: incidence rate 3.8/100,000/year (95% confidence interval 2.5-5.1/100,000/year).Conclusion, This study illustrates dramatic differences in incidence and prevalence rates in the UK, depending on ethnic group and irrespective of place of birth.