BAND HETEROTOPIAS - A NEWLY RECOGNIZED NEURONAL MIGRATION ANOMALY
BAND HETEROTOPIAS - A NEWLY RECOGNIZED NEURONAL MIGRATION ANOMALY
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DOI：
10.1148/radiology.171.2.2468173
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发表时间：
1989-05-01
期刊：
影响因子：
19.7
通讯作者：
BOYER, RS
中科院分区：
文献类型：
--
作者：
BARKOVICH, AJ;JACKSON, DE;BOYER, RS
本文描述了5例侧脑室和大脑皮层之间有连续的异位神经元带的患者。所有患者均出现难治性癫痫发作和中度至重度发育迟缓。这种异常的识别是困难的，因为它的对称性和最小的异常的大脑皮层的旋转模式。讨论了异常的可能胚胎发生。鉴别这些带异位是重要的，因为顽固性癫痫发作障碍和预后差的病人。
Five patients with a continuous band of heterotopic neurons between the lateral ventricles and the cerebral cortex are described. All patients presented with intractable seizures and moderate-to-severe developmental delay. The identification of this anomaly is difficult because of its symmetry and the minimal abnormality of the gyral pattern of the cortex. The possible embryogenesis of the anomaly is discussed. The identification of these band hetertopias is important because of the intractable nature of the seizure disorder and the poor prognosis for the patient.