Isoniazid metabolism and hepatotoxicity.
Isoniazid metabolism and hepatotoxicity.
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DOI：
10.1016/j.apsb.2016.07.014
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发表时间：
2016-09
影响因子：
14.5
通讯作者：
Ma, Xiaochao
中科院分区：
文献类型：
--
作者：
Wang, Pengcheng;Pradhan, Komal;Zhong, Xiao-bo;Ma, Xiaochao
异烟肼（INH）对结核病的管理非常有效。但是，它会导致肝损伤，甚至肝衰竭。INH代谢被认为与INH诱导的肝损伤有关。本文综述了INH的代谢途径，并讨论了它们与INH引起的肝损伤的关系。异烟肼（INH）对结核病的管理非常有效。但是，它会导致肝损伤，甚至肝衰竭。INH代谢被认为与INH诱导的肝损伤有关。本文综述了INH的代谢途径，并讨论了它们与INH引起的肝损伤的关系。
Isoniazid (INH) is highly effective for the management of tuberculosis. However, it can cause liver injury and even liver failure. INH metabolism has been thought to be associated with INH-induced liver injury. This review summarized the metabolic pathways of INH and discussed their associations with INH-induced liver injury. Isoniazid (INH) is highly effective for the management of tuberculosis. However, it can cause liver injury and even liver failure. INH metabolism has been thought to be associated with INH-induced liver injury. This review summarized the metabolic pathways of INH and discussed their associations with INH-induced liver injury.
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影响因子：
4.9
作者：
Conte, JE;Golden, JA;Zurlinden, E
通讯作者：
Zurlinden, E
影响因子：
2.9
作者：
Azuma, Junichi;Ohno, Masako;Kubota, Ryuji;Yokota, Soichiro;Nagai, Takayuki;Tsuyuguchi, Kazunari;Okuda, Yasuhisa;Takashima, Tetsuya;Kamimura, Sayaka;Fujio, Yasushi;Kawase, Ichiro
通讯作者：
Kawase, Ichiro
DOI：
10.1515/dmdi.2011.016
发表时间：
2011-10-01
期刊：
Drug Metabolism and Drug Interactions
影响因子：
--
作者：
Chen Bing;Cao Xiaomei;Li Jinheng
通讯作者：
Li Jinheng
影响因子：
3.2
作者：
Cho, Hyun-Jung;Koh, Won-Jung;Lee, Soo-Youn
通讯作者：
Lee, Soo-Youn
影响因子：
3.7
作者：
Ascenzi, Paolo;Coletta, Andrea;Coletta, Massimo
通讯作者：
Coletta, Massimo