Positive affect treatment targets reward sensitivity: A randomized controlled trial.
Positive affect treatment targets reward sensitivity: A randomized controlled trial.
复制标题
积极情感治疗目标奖励敏感性:一项随机对照试验。
DOI:
10.1037/ccp0000805
复制
发表时间:
2023
影响因子:
5.9
通讯作者:
Ritz,Thomas
中科院分区:
文献类型:
--
作者:
Craske,MichelleG;Meuret,AliciaE;Echiverri-Cohen,Aileen;Rosenfield,David;Ritz,Thomas
ObjectiveDetermine whether a novel psychosocial treatment for positive affect improves clinical status and reward sensitivity more than a form of cognitive behavioral therapy that targets negative affect and whether improvements in reward sensitivity correlate with improvements in clinical status.MethodIn this assessor-blinded, parallel-group, multisite, two-arm randomized controlled clinical superiority trial, 85 treatment-seeking adults with severely low positive affect, moderate-to-severe depression or anxiety, and functional impairment received 15 weekly individual therapy sessions of positive affect treatment (PAT) or negative affect treatment (NAT). Clinical status measures were self-reported positive affect, interviewer-rated anhedonia, and self-reported depression and anxiety. Target measures were eleven physiological, behavioral, cognitive, and self-report measures of reward anticipation-motivation, response to reward attainment, and reward learning. All analyses were intent-to-treat.ResultsCompared to NAT, individuals receiving PAT achieved superior improvements in the multivariate clinical status measures at posttreatment, b=. 37, 95% CI [. 15,. 59], t (109)= 3.34, p=. 001, q=. 004, d=. 64. Compared to NAT, individuals receiving PAT also achieved higher multivariate reward anticipation-motivation, b=. 21, 95% CI [. 05,. 37], t (268)= 2.61, p=. 010, q=. 020, d=. 32, and higher multivariate response to reward attainment, b=. 24, 95% CI [. 02,. 45], t (266)= 2.17, p=. 031, q=. 041, d=. 25, at posttreatment. Measures of reward learning did not differ between the two groups. Improvements in reward anticipation-motivation and in response to reward attainment correlated with improvements in the clinical status measures.ConclusionsTargeting positive affect results in superior improvements in clinical status and reward sensitivity than targeting negative affect. This is the first demonstration of differential target engagement across two psychological interventions for anxious or depressed individuals with low positive affect.(PsycInfo Database Record (c) 2023 APA, all rights reserved)