Detection of high rates of in-village transmission of Leishmania donovani in eastern Sudan

Detection of high rates of in-village transmission of Leishmania donovani in eastern Sudan
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DOI:
10.1016/j.actatropica.2004.06.001
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发表时间:
2004-09-01
期刊:
影响因子:
2.7
通讯作者:
Elnaiem, DA
Elnaiem, DA
中科院分区:
医学2区
文献类型:
--
作者:
Hassan, MM;Elraba'a, FMA;Elnaiem, DA

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内脏利什曼病(VL;黑热病),由杜氏利什曼原虫引起,由东方白蛉传播。是苏丹东部和南部的一个主要健康问题,在那里,最近的疾病流行夺去了10万多人的生命(Eschann等人,1996; Elnaiem等人,2003年)。先前在这些疫源地进行的研究表明,VL的载体主要在以金合欢和埃及藤壶树为主的林地中生长。Hoogstraal和Heyneman,1969年; Schorscher和戈里斯,1992年; Elnaiem等人,1997; Thomson等人,1999年)。在这个栖息地,我们发现了高感染率的L。donovani在东方对虾中的作用(Elnaiem等,1998),并提供了证据表明埃及猫鼬(Herpestes ichelon)是该寄生虫的森林储库宿主(Elnaiem等,2001年)。
Visceral leishmaniasis (VL; kala azar), caused by Leishmania donovani and transmitted by Phlebotmus orientalis. is a major health problem in eastern and southern Sudan, where recent epidemics of the disease claimed the lives of more than 100,000 people (Seamann et al., 1996; Elnaiem et al., 2003). Previous studies carried out in these foci demonstrated that the vector of VL thrives mainly in woodland dominated by Acacia seyal and Balanites aegyptiaca trees Hoogstraal and Heyneman, 1969; Schorscher and Goris, 1992; Elnaiem et al., 1997; Thomson et al., 1999). In this habitat, we found high rates of infection of L. donovani in P orientalis (Elnaiem et al., 1998) and provided evidence that the Egyptian mongoose (Herpestes ichneumon) is a silvatic reservoir host of the parasite (Elnaiem et al., 2001).