Predictive value of electron beam computed tomography of the coronary arteries - 19-month follow-up of 1173 asymptomatic subjects
Predictive value of electron beam computed tomography of the coronary arteries - 19-month follow-up of 1173 asymptomatic subjects
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DOI：
10.1161/01.cir.93.11.1951
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发表时间：
1996-06-01
期刊：
影响因子：
37.8
通讯作者：
Guerci, AD
中科院分区：
文献类型：
--
作者：
Arad, Y;Spadaro, LA;Guerci, AD
背景冠状动脉电子束计算机断层扫描（EBCT）通过测量冠状动脉壁中的钙沉积来检测冠状动脉粥样硬化性疾病。EBCT衍生的冠状动脉钙（CAC）分数与潜在的冠状动脉diseases.Methods和结果的严重程度相关，我们随访了1173例无症状患者接受EBCT在1993年9月和1994年3月。在平均19个月的随访中，18例受试者发生了26起心血管事件：1例死亡，7例心肌梗死，8例冠状动脉旁路移植术，9例冠状动脉血管成形术和1例非出血性卒中。对于CAC评分阈值100、160和680，EBCT的敏感性分别为89%、89%和50%，特异性分别为77%、52%和95%。比值比为20.0 ~ 35.4（P
Background Coronary electron beam computed tomography (EBCT) detects atherosclerotic coronary artery disease by measuring calcium deposition in the walls of coronary arteries. EBCT-derived coronary artery calcium (CAC) scores correlate with the severity of underlying coronary artery disease.Methods and Results We followed 1173 asymptomatic patients who underwent EBCT between September 1993 and March 1994. During average follow-up of 19 months, 18 subjects had 26 cardiovascular events: 1 death, 7 myocardial infarctions, 8 coronary artery bypass graft procedures, 9 coronary angioplasties, and 1 nonhemorrhagic stroke. For CAC score thresholds of 100, 160, and 680, EBCT had sensitivities of 89%, 89%, and 50% and specificities of 77%, 52%, and 95%, respectively. Odds ratios ranged from 20.0 to 35.4 (P