Depression and 1-year prognosis in unstable angina
Depression and 1-year prognosis in unstable angina
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DOI：
10.1001/archinte.160.9.1354
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发表时间：
2000-05-08
影响因子：
--
通讯作者：
Théroux, P
中科院分区：
文献类型：
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作者：
Lespérance, F;Frasure-Smith, N;Théroux, P
背景：抑郁症在急性心肌梗死后很常见，并且与至少18个月的死亡风险增加相关。抑郁症的患病率和预后的影响，不稳定型心绞痛患者，谁占了相当大的一部分急性冠脉综合征的入院，尚未examined.Methods：在医院进行了采访与430例不稳定型心绞痛患者出院前不需要冠状动脉搭桥手术。抑郁症是使用21项自我报告贝克抑郁量表进行评估，并定义为10分或更高。主要结果是1年心源性死亡或非致命性myocardialinfarct.Results：贝克抑郁量表确定抑郁症患者的41.4%。抑郁患者比其他患者更容易发生心源性死亡或非致命性心肌梗死（比值比，4.68; 95%可信区间，1.9-11.27; P
Background: Depression is common after acute myocardial infarction and is associated with an increased risk of mortality for at least 18 months. The prevalence and prognostic impact of depression in patients with unstable angina, who account for a substantial portion of acute coronary syndrome admissions, have not been examined.Methods: Interviews were carried out in hospital with 430 patients with unstable angina who did not require coronary artery bypass surgery before hospital discharge. Depression was assessed using the 21-item self-report Beck Depression Inventory and was defined as a score of 10 or higher. The primary outcome was 1-year cardiac death or nonfatal myocardial infarction.Results: The Beck Depression Inventory identified depression in 41.4% of patients. Depressed patients were more likely to experience cardiac death or nonfatal myocardial infarction than other patients (odds ratio, 4.68; 95% confidence interval, 1.9-11.27; P