Relationship between retinal sensitivities and optical coherence tomographic findings in eyes with myopic chorioretinal atrophy
Relationship between retinal sensitivities and optical coherence tomographic findings in eyes with myopic chorioretinal atrophy
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DOI：
10.1177/11206721211008038
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发表时间：
2021-04-07
影响因子：
1.7
通讯作者：
Yamamoto, Shuichi
中科院分区：
文献类型：
--
作者：
Kakisu, Masato;Baba, Takayuki;Yamamoto, Shuichi
目的：探讨近视性脉络膜视网膜萎缩(CRA)患者视网膜敏感度与光感受器椭圆区(EZ)完整性之间是否存在显著相关性。我们还确定了视网膜敏感度与视网膜和脉络膜厚度之间的相关性的意义。方法：回顾分析6例10眼近视性CRA患者的临床资料。在6次扫描的37个点的光谱域光学相干断层扫描(OCT)图像中确定EZ的完整性，对应于MP-3微视野计测量视网膜敏感度的位置。中间视视网膜敏感度测定在中心16度以内。确定EZ的完整性与中间视视网膜敏感度的相关性的意义。测定了视网膜厚度和脉络膜厚度与视网膜敏感度的关系。结果：患者平均年龄70.0±6.7岁，眼轴平均29.2 mm。有EZ的中视敏感度显著高于无EZ的中视敏感度(P<；0.01)。中视敏感度与视网膜厚度(p<；0.01，r=0.30)和脉络膜厚度(p<；0.01，r=0.23)显著相关。结论：近视性CRA眼的中间视敏感度与EZ的完整性之间存在显著的相关性，说明中间视敏感度可以用来评估近视性CRA的光感受器的完整性。
Purpose: To determine whether there is a significant correlation between the retinal sensitivity and the integrity of the ellipsoid zone (EZ) of the photoreceptors in eyes with myopic chorioretinal atrophy (CRA). We also determined the significance of the correlation between the retinal sensitivity and the retinal and choroidal thicknesses. Methods: The medical records of 10 eyes of six subjects with myopic CRA were reviewed. The integrity of the EZ was determined in the spectral-domain optical coherence tomographic (OCT) images at 37 points of six scans corresponding to the locations where the retinal sensitivities were measured by MP-3 microperimetry. The mesopic retinal sensitivities were determined within the central 16 degrees. The significance of the correlations between the integrity of the EZ and the mesopic retinal sensitivities was determined. The relationships between the retinal and choroidal thickness and the retinal sensitivity were also determined. Results: The average age of the patients was 70.0 +/- 6.7 years, and the average axial length of the eye was 29.2 mm. The mesopic sensitivities at the points where the EZ was present were significantly higher than those where the EZ was absent (p < 0.01). The mesopic sensitivity was significantly correlated with the retinal thickness (p < 0.01, r = 0.30) and the choroidal thickness (p < 0.01, r = 0.23). Conclusions: The significant correlation between the mesopic retinal sensitivity and the integrity of the EZ indicates that the mesopic sensitivities can be used to assess the integrity of the photoreceptors in eyes with myopic CRA.