Origin of the additional chromosome in Down's syndrome: a study of 20 families.
Origin of the additional chromosome in Down's syndrome: a study of 20 families.
复制标题
唐氏综合症附加染色体的起源：对 20 个家庭的研究。
DOI：
10.1136/jmg.17.5.363
复制
发表时间：
1980
影响因子：
4
通讯作者：
M. H. Callow
中科院分区：
文献类型：
--
作者：
D. F. Roberts;M. H. Callow
In 20 families with a Down's syndrome child, heteromorphism of chromosome 21 was sought in the parents and proband. Information on the meiotic division and the parent of origin was given in 16 families, the majority of errors being maternal in origin, predominantly at meiosis I, though the paternal contribution is also appreciable. Probabilities of parental and meiotic division origin are calculated.
