Sudden cardiac death in patients with diabetes.

Sudden cardiac death in patients with diabetes.
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DOI:
10.1007/s11892-004-0022-8
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发表时间:
2004-06-01
影响因子:
4.2
通讯作者:
Bigger, J Thomas
Bigger, J Thomas
中科院分区:
医学2区
文献类型:
--
作者:
El-Atat, Fadi A;McFarlane, Samy I;Bigger, J Thomas

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心脏性猝死(SCD)每年影响美国超过45万人。所涉及的机制知之甚少。目前已知的预测因素包括传统的冠心病危险因素、心电图异常、心脏自主神经病变、左心室肥大、心肌病和传导异常。糖尿病和葡萄糖耐量受损具有特别重要的意义,因为它们的患病率增加,达到流行病的比例,并且患有这些疾病的人中SCD的风险增加。本文综述了目前SCD的预测因素,重点是糖尿病患者,希望为医生和研究人员提供更好的理解和坚实的基础,进一步研究这一重要的过早死亡原因。
Sudden cardiac death (SCD) affects over 450,000 people in the United States annually. The mechanisms involved are poorly understood. The predictors currently known include traditional coronary heart disease risk factors, electrocardiographic abnormalities, cardiac autonomic neuropathy, left ventricular hypertrophy, cardiomyopathy, and conduction abnormalities. Diabetes mellitus and impaired glucose tolerance are of special importance due to their increased prevalence reaching epidemic proportions and the elevated risk of SCD in people with these disorders. This article reviews the current predictors of SCD with a focus on people with diabetes, hoping to offer physicians and researchers a better understanding of and a solid ground for further needed research on this important cause of premature death.