Exposure to ambient air pollution and visual impairment in children: A nationwide cross-sectional study in China.
Exposure to ambient air pollution and visual impairment in children: A nationwide cross-sectional study in China.
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DOI：
10.1016/j.jhazmat.2020.124750
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发表时间：
2020-12
影响因子：
13.6
通讯作者：
Bo-yi Yang;Yuming Guo;Z. Zou;Zhaohuan Gui;Wen-wen Bao;L. Hu;Gongbo Chen;J. Jing;Jun Ma;Shanshan Li;Yinghua Ma;Yajun Chen;G. Dong
中科院分区：
文献类型：
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作者：
Bo-yi Yang;Yuming Guo;Z. Zou;Zhaohuan Gui;Wen-wen Bao;L. Hu;Gongbo Chen;J. Jing;Jun Ma;Shanshan Li;Yinghua Ma;Yajun Chen;G. Dong
关于暴露在空气污染和视力损害中的证据很少。我们评估了环境空气污染与中国学龄儿童视力损害和视力水平的关系。我们从中国的7个省市招募了61,995名儿童。使用机器学习方法测量了空气污染物(即空气动力学直径为≤的颗粒物为1.0微米[PM1]、≤为2.5微米[PM2.5]和10微米[PM10]以及二氧化氮[NO2])的浓度。使用标准方案测量视力水平。我们使用SAS Proc SURVELOGISTIC来评估空气污染与视力损害之间的关系。PM1、PM2.5、PM10和NO2的四分位数范围增加与视力障碍的风险增加相关，分别为1.133(95%可信区间，1.035-1.240)、1.267(95%可信区间，1.082-1.484)、1.142(95%可信区间，1.019-1.281)和1.276倍(95%可信区间，1.173-1.388)，而且这种关联在男孩、年龄较大、生活在农村地区、父母教育水平较低或吸烟的儿童中更强。与他们的同行相比。这些结果表明，暴露在空气污染中与视力损害的几率呈正相关，这种关联可能会受到儿童的年龄、性别、居民区以及父母教育水平和吸烟的影响。
Evidence concerning exposure to air pollution and visual impairment is scarce. We evaluated the associations of ambient air pollution with visual impairment and visual acuity levels in Chinese schoolchildren. We recruited 61,995 children from 7 provinces/municipalities across China. Concentrations of air pollutants (i.e., particulate matter with an aerodynamic diameter of ≤ 1.0 µm [PM1], ≤ 2.5 µm [PM2.5], and 10 µm [PM10] as well as nitrogen dioxides [NO2]) were measured using machine learning methods. Visual acuity levels were measured using standard protocols. We used SAS PROC SURVEYLOGISTIC to assess the association between air pollution and visual impairment. An interquartile range increase in PM1, PM2.5, PM10, and NO2was associated with a 1.133- (95% CI, 1.035-1.240), 1.267- (95% CI, 1.082-1.484), 1.142- (95% CI, 1.019-1.281), and 1.276-fold (95% CI, 1.173-1.388) increased odds of visual impairment, and the associations were stronger in children being boys, older, living in rural areas, and born to parents who had a lower educational level or smoked, compared to their counterparts. These results suggest that exposure to air pollution were positively associated with the odds of visual impairment, and the association may be modified by children’s age, sex, and residential area as well as parental education level and cigarette smoking.