Single breath diffusing capacity in a representative sample of the population of Michigan, a large industrial state. Predicted values, lower limits of normal, and frequencies of abnormality by smoking history.
Single breath diffusing capacity in a representative sample of the population of Michigan, a large industrial state. Predicted values, lower limits of normal, and frequencies of abnormality by smoking history.
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工业大州密歇根州人口代表性样本的单次呼吸扩散能力。
DOI：
10.1164/arrd.1983.127.3.270
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发表时间：
1983
期刊：
影响因子：
--
通讯作者：
I. Selikoff
中科院分区：
文献类型：
--
作者：
A. Miller;J. Thornton;R. Warshaw;H. Anderson;A. Teirstein;I. Selikoff
许多关于单次呼气CO弥散量(DlCOsb)的预测公式是基于小的、选定的人群，并且没有考虑吸烟的影响。我们对582名白人成年人进行了这项测试，他们是密歇根州人口的分层随机样本的一部分，密歇根州是一个大型工业州。有完整临床信息和正常血红蛋白浓度的511名受试者的数据提供了预测方程和当前吸烟者、既往吸烟者和不吸烟者的95%下限。这些是通过对整个州的总体人口进行抽样而获得的第一个方程。不同吸烟类别间DlCOsb水平有显著差异。为了获得关于DlCOsb在普通人群中被报告为异常的频率的信息，对所有582名受试者的测试结果与参考值进行了比较。使用不考虑吸烟的公式，将30%的男性吸烟者和28%的女性吸烟者归类为“异常”，而吸烟的男性和女性吸烟者的比例分别为30%和28%。
Many predictive equations for the single breath CO diffusing capacity (DlCOsb) are based on small, selected populations and do not account for the effect of cigarette smoking. We performed this test on 582 white adults who were part of a stratified random sample of the population of Michigan, a large industrial state. Data on 511 subjects who had full clinical information and normal hemoglobin concentration provided prediction equations and lower 95% limits for current cigarette smokers, ex-smokers, and nonsmokers. These are the first equations, obtained by sampling the general population of an entire state. Significant differences in the level of DlCOsb were found between smoking categories. To obtain information on the frequency with which DlCOsb would be reported as abnormal in a general population, the test results for all 582 subjects were compared with reference values. Use of equations that do not take, smoking into account classified 30% of the male and 28% of the female smokers as “abnormal,” whe...