Quantitative imaging of perfusion using a single subtraction (QUIPSS and QUIPSS II)
Quantitative imaging of perfusion using a single subtraction (QUIPSS and QUIPSS II)
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DOI：
10.1002/mrm.1910390506
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发表时间：
1998-05-01
影响因子：
3.3
通讯作者：
Frank, LR
中科院分区：
文献类型：
--
作者：
Wong, EC;Buxton, RB;Frank, LR
在脉冲动脉自旋标记（ASL）技术EPISTAR、PICORE和FAIR中，对流入的血液首先被标记然后不被标记的两个图像进行减法产生灌注的定性图。该图不是定量的一个重要原因是，血液从标记区域到成像切片的传输中存在空间变化的延迟，这不能从单次减影中测量。我们在这里介绍两个修改的脉冲ASL（QUIPSS和QUIPSS II），避免了这个问题，通过施加额外的饱和脉冲来控制标记的推注的持续时间，使该技术相对不敏感的传输延迟和改善定量灌注。
In the pulsed arterial spin labeling (ASL) techniques EPISTAR, PICORE, and FAIR, subtraction of two images in which inflowing blood is first tagged and then not tagged yields a qualitative map of perfusion. An important reason this map is not quantitative is that there is a spatially varying delay in the transit of blood from the tagging region to the imaging slice that cannot be measured from a single subtraction. We introduce here two modifications of pulsed ASL (QUIPSS and QUIPSS II) that avoid this problem by applying additional saturation pulses to control the time duration of the tagged bolus, rendering the technique relatively insensitive to transit delays and improving the quantitation of perfusion.