Association of Cytomegalovirus (CMV) DNAemia With Long-Term Mortality in a Randomized Trial of Preemptive Therapy and Antiviral Prophylaxis for Prevention of CMV Disease in High-Risk Donor Seropositive, Recipient Seronegative Liver Transplant Recipients.

Association of Cytomegalovirus (CMV) DNAemia With Long-Term Mortality in a Randomized Trial of Preemptive Therapy and Antiviral Prophylaxis for Prevention of CMV Disease in High-Risk Donor Seropositive, Recipient Seronegative Liver Transplant Recipients.
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在一项针对高风险供体血清阳性、受者血清阴性肝移植受者中预防 CMV 疾病的先发性治疗和抗病毒预防的随机试验中,巨细胞病毒 (CMV) DNA 血症与长期死亡率的关联。

DOI:
10.1093/cid/ciad643
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发表时间:
2024
期刊:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
影响因子:
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通讯作者:
Limaye,AjitP
Limaye,AjitP
中科院分区:
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文献类型:
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作者:
Kumar,Lakshin;Dasgupta,Sayan;Murray-Krezan,Cristina;Singh,Nina;Rakita,RobertM;Fisher,CynthiaE;Limaye,AjitP

文献摘要

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在一项针对D+R-肝移植受者CMV先发制人治疗与抗病毒预防的随机试验中,CMV DNAemia与长期死亡率相关性的事后分析显示,干预后CMV DNAemia与研究组调整后的死亡率增加相关。
In a post-hoc analysis of the association of CMV DNAemia with long-term mortality in a randomized trial of CMV preemptive therapy vs. antiviral prophylaxis in D+R- liver transplant recipients, post-intervention CMV DNAemia was associated with increased mortality after adjusting for study arm.