An improved rat model to study efficacy of drugs for treatment or prophylaxis of Pneumocystis carinii pneumonia.
An improved rat model to study efficacy of drugs for treatment or prophylaxis of Pneumocystis carinii pneumonia.
复制标题
改进的大鼠模型，用于研究治疗或预防卡氏肺孢子虫肺炎药物的功效。
DOI：
10.1111/j.1550-7408.1989.tb02712.x
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发表时间：
1989
期刊：
影响因子：
--
通讯作者：
Smith,JW
中科院分区：
文献类型：
--
作者：
Barlett,MS;Fishman,JA;Durkin,MM;Queener,SF;Smith,JW
用免疫功能低下的大鼠经气管接种P.描述了卡那霉素化疗和预防试验。未治疗动物的感染比治疗动物重;该模型为P。Cariniiis推荐。
The use of immunocompromised rats transtracheally inoculated withP. cariniiin chemotherapy and prophylaxis testing is described. Infections in untreated animals were heavier than in treated animals; this model forP. cariniiis recommended.