Differences between estimates and measured PaCO2 during rest and exercise in older subjects.

Differences between estimates and measured PaCO2 during rest and exercise in older subjects.
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老年受试者休息和运动期间 PaCO2 估计值与测量值之间的差异。

DOI:
10.1152/jappl.1997.83.1.312
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发表时间:
1997
期刊:
Journal of applied physiology (Bethesda, Md. : 1985)
影响因子:
--
通讯作者:
Babb,TG
Babb,TG
中科院分区:
--
文献类型:
--
作者:
Williams,JS;Babb,TG

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Williams, J. S., and T. G. Babb.Differences between estimates and measuredduring rest and exercise in older subjects.J. Appl. Physiol.83(1): 312–316, 1997.—Arterial() has been estimated during exercise with good accuracy in younger individuals by using the Jones equation (PJco2) (J. Appl. Physiol.47: 954–960, 1979). The purpose of this project was to determine the utility of estimatingfrom end-tidal() or PJco2at rest, ventilatory threshold (V˙Th), and maximal exercise (Max) in older subjects.was determined from respired gases simultaneously (MGA 1100) with arterial blood gases (radial arterial catheter) in 12 older and 11 younger subjects at rest and during exercise. Mean differences were analyzed with pairedt-tests, and relationships between the estimatedvalues and the actual values ofwere determined with correlation coefficients. In the older subjects,was not significantly different fromat rest (−1.2 ± 4.3 Torr), V˙Th (0.4 ± 2.5), or Max (−0.8 ± 2.7), and the two were significantly (P< 0.05) correlated atV˙th (r= 0.84) and Max (r= 0.87) but not at rest (r= 0.47). PJco2was similar toat rest (−1.0 ± 3.9) and V˙th (−1.3 ± 2.3) but significantly lower at Max (−3.0 ± 2.6), and the two were significantly correlated at V˙th (r= 0.86) and Max (r= 0.80) but not at rest (r= 0.54).was significantly higher thanduring exercise in the younger subjects but similar toat rest. PJco2was similar toat rest andV˙th but significantly lower at Max in younger subjects. In conclusion, our data demonstrate thatduring exercise is better estimated bythan by PJco2in older subjects, contrary to what is observed in younger subjects. This appears to be related to the finding thatdoes not exceedduring exercise in older subjects, as occurs in the younger subjects. However,at rest is best estimated by PJco2in both younger and older subjects.