Sequence analyses of a lipoprotein conserved with bacterial actins responsible for swimming motility of wall-less helical Spiroplasma.
Sequence analyses of a lipoprotein conserved with bacterial actins responsible for swimming motility of wall-less helical Spiroplasma.
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DOI：
10.17912/micropub.biology.000713
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发表时间：
2023
影响因子：
--
通讯作者：
Miyata, Makoto
中科院分区：
文献类型：
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作者：
Takahashi, Daichi;Miyata, Makoto
螺旋体是一种致病或共生的细胞壁缺陷螺旋细菌。螺旋体特异的蛋白原纤维和五类细菌肌动蛋白MreB1-5参与了螺旋带结构，负责螺旋细胞的形态和游泳运动。在编码mreB S的基因座上发现了一种假想蛋白Spe_1229第7蛋白的基因。在本研究中，我们用电子计算机方法对第7蛋白进行了鉴定，发现它可能是一种脂蛋白，其基因编码在mreB3下游，并在螺旋体的一个分支中保守。
Spiroplasma is a genus of pathogenic or commensal cell-wall-deficient helical bacterium. Spiroplasma -specific protein fibril and five classes of bacterial actins, MreB1–5, are involved in a helical ribbon structure responsible for helical-cell morphology and swimming motility. A gene for a hypothetical protein—SPE_1229, 7th protein—has been found in the locus coding mreB s. In this study, we characterized the 7th protein using in silico methods and found that it could be a lipoprotein whose gene is encoded downstream of mreB3 and conserved in a clade of Spiroplasma .