Fluctuation AnaLysis CalculatOR: a web tool for the determination of mutation rate using Luria-Delbruck fluctuation analysis

Fluctuation AnaLysis CalculatOR: a web tool for the determination of mutation rate using Luria-Delbruck fluctuation analysis
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DOI:
10.1093/bioinformatics/btp253
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发表时间:
2009-06-15
期刊:
影响因子:
5.8
通讯作者:
Singh, Keshav K.
Singh, Keshav K.
中科院分区:
生物学3区
文献类型:
--
作者:
Hall, Brandon M.;Ma, Chang-Xing;Singh, Keshav K.

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Fluctuation AnaLysis CalculatOR(英语:Fluctuation AnaLysis CalculatOR)程序是一个网络工具,设计用于Luria-Delbruck波动分析,以计算细菌和酵母中各种突变测定的频率和速率。该程序提供三种计算方法:(i)Ma-Sandri-Sarkar最大似然估计(MSS-MLE)方法,(ii)中位数(LC)的Lea-Coulson方法和(iii)频率。
The program Fluctuation AnaLysis CalculatOR (FALCOR) is a web tool designed for use with Luria-Delbruck fluctuation analysis to calculate the frequency and rate from various mutation assays in bacteria and yeast. Three calculation methods are available through this program: (i) Ma-Sandri-Sarkar Maximum Likelihood Estimator (MSS-MLE) method, (ii) Lea-Coulson method of the median (LC) and (iii) frequency.