Hepatitis delta virus in intravenous drug users in Kuala Lumpur.
Hepatitis delta virus in intravenous drug users in Kuala Lumpur.
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吉隆坡静脉吸毒者感染丁型肝炎病毒。
DOI：
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发表时间：
1994
期刊：
影响因子：
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通讯作者：
C. S. Kek
中科院分区：
文献类型：
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作者：
G. Duraisamy;H. Zuridah;Y. Ariffin;C. S. Kek
丁型肝炎病毒(HDV)是一种含有RNA的病毒，需要乙肝病毒(乙肝病毒)提供包膜蛋白。HDV仅在存在乙肝病毒的情况下才会感染人类，无论是作为重叠感染还是作为重叠感染在乙肝病毒携带者中。在存在乙肝病毒感染的情况下，HDV可能会比单独由乙肝病毒引起的肝损害更严重。对1990~1992年吉隆坡医院血液服务中心(BSC)筛查的44份男性静脉吸毒者的血清标本进行了HDV感染的研究。大多数(39人)年龄在20岁到39岁之间。最小的19岁，最大的61岁。有25名马来人，13名中国人，5名印度人和1名阿尔巴尼亚人。44例吸毒者中15例(34%)检出抗丁型肝炎抗体(抗-HDV)。结果表明，与1985年未检出Delta抗体的监测结果，以及1986年和1989年的监测结果(分别为17.8%和20%)相比，静脉吸毒者的Delta感染明显增加。
The hepatitis delta virus (HDV) is an RNA containing virus that requires hepatitis B virus (HBV) to supply the envelope proteins. HDV only infect man in the presence of HBV, either as a coinfection or as superinfection in HBV carriers. In the presence of hepatitis B infection, the HDV may cause more severe liver damage than that caused by the hepatitis B virus alone. HDV infection was studied in 44 HBsAg positive serum samples collected from male intravenous drug users sent for screening to the Blood Services Centre (BSC), Hospital Kuala Lumpur (HKL) between 1990 and 1992. The majority (39) were in the 20 to 39 age group. The youngest was 19 years old and the oldest was 61 years old. There were 25 Malays, 13 Chinese, five Indians and one Albanian. Anti hepatitis delta antibody (Anti-HDV) was detected in 15 out of 44 (34%) of the drug addicts. These results shows an increased in delta infection in HBsAg positive intravenous drug addicts compared to the surveillance results in 1985 when no delta antibodies were detected, and the 1986 and 1989 surveillance which showed 17.8% and 20% delta antibody positivity respectively.