A “second messenger” for Vitamin D
A “second messenger” for Vitamin D
复制标题
维生素 D 的“第二信使”
DOI：
10.1016/0014-5793(69)80051-7
复制
发表时间：
1969
期刊：
影响因子：
3.5
通讯作者：
E. Holdsworth
中科院分区：
文献类型：
--
作者：
E. Neville;E. Holdsworth
维生素D，可以被认为是一种激素产生的皮肤，储存在肝脏，并从那里释放，在各种网站在体内，特别是在小肠，以帮助钙的吸收[11.许多激素被认为是通过“第二信使”发挥作用[2]，通常是环状3 '，5'-腺苷一磷酸（环AMP），了解维生素D（激素）在影响钙和磷酸盐代谢期间是否也使用这种第二信使是有意义的。这封信报道了维生素D3对腺苷酸环化酶的影响，以及环腺苷酸衍生物对鸡小肠钙转运的影响。
Vitamin D, can be considered to be a hormone produced by the skin, stored in the liver, and released from there to act at a variety of sites in the body in particular at the small intestine to aid the absorption of calcium [11. Many hormones are considered to function via a “second messenger”[2] usually cyclic 3’, 5’-adenosine monophosphate (cyclic AMP) and it is of interest to know whether vitamin D,(hormone) also uses this second messenger during its effect on calcium and phosphate metabolism. This letter reports the effect of vitamin D3 on adenyl cyclase and on the effect of a derivative of cyclic AMP on calcium transport across the small intestine of the chick.