Purification and properties of a new coupling factor required for oxidative phosphorylation in silicotungstate-treated submitochondrial particles.
Purification and properties of a new coupling factor required for oxidative phosphorylation in silicotungstate-treated submitochondrial particles.
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硅钨酸盐处理的亚软骨颗粒氧化磷酸化所需的新偶联因子的纯化和性质。
DOI：
10.1016/s0021-9258(19)45436-7
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发表时间：
1972
期刊：
影响因子：
--
通讯作者：
J. Fessenden
中科院分区：
文献类型：
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作者：
J. Fessenden
从牛心肌线粒体中纯化了一种热稳定的、胰蛋白酶不稳定的偶联因子（F6）。在几种大小相似但净电荷不同的同工蛋白中发现了F6活性。F6是氧化磷酸化和32 Pi-ATP交换所必需的，也是琥珀酸还原DPN和ATP转氢所必需的。
A heat-stable, trypsin-labile coupling factor (F6) has been purified from bovine heart mitochondria. F6activity has been found in several isoproteins of similar size, but differing in net charge. F6is required for oxidative phosphorylation and32Pi—ATP exchange, as well as for DPN reduction by succinate and transhydrogenation with ATP as an energy source.