Increased neutrophil gelatinase-associated lipocalin (NGAL) promotes airway remodelling in chronic obstructive pulmonary disease.

Increased neutrophil gelatinase-associated lipocalin (NGAL) promotes airway remodelling in chronic obstructive pulmonary disease.
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中性粒细胞明胶酶相关脂质运载蛋白 (NGAL) 的增加可促进慢性阻塞性肺疾病的气道重塑。

DOI:
10.1042/cs20170096
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发表时间:
2017-06
期刊:
影响因子:
6
通讯作者:
Xin Yao
Xin Yao
中科院分区:
医学2区
文献类型:
--
作者:
Yujie Wang;Man Jia;Xiaoyi Yan;Limin Cao;Peter Barnes;Ian Adcock;Mao Huang;Xin Yao

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气道重塑是慢性阻塞性肺疾病(COPD)的重要组成部分。来自中性粒细胞的中性粒细胞明胶酶相关脂质运载蛋白(NGAL)可能驱动COPD上皮-间质转化(EMT)。NGAL的表达定量,
Airway remodelling is an important component of chronic obstructive pulmonary disease (COPD). Neutrophil gelatinase-associated lipocalin (NGAL) from neutrophils may drive COPD epithelial-mesenchymal transition (EMT). NGAL expression was quantified in the
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