Patterns and rate of adherence to glaucoma therapy using an electronic dosing aid
Patterns and rate of adherence to glaucoma therapy using an electronic dosing aid
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DOI：
10.1038/eye.2010.27
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发表时间：
2010-08-01
期刊：
影响因子：
3.9
通讯作者：
Henson, D. B.
中科院分区：
文献类型：
--
作者：
Ajit, R. R.;Fenerty, C. H.;Henson, D. B.
目的和目的确定曲伏前列素滴眼液使用曲伏前列素给药辅助（TDA）的模式和依从率，并提出一种以图形方式显示依从性数据的方法。方法对曲伏前列素单药治疗的患者进行前瞻性观察队列研究。给患者分配TDA，并在使用约3个月后进行随访。数据从TDA下载到计算机中进行分析。分析使用剂量间隔（每次给药之间的时间）来观察第4天和第75天之间的依从性。结果共邀请100例患者参与，53例患者同意，37例患者获得完整的TDA数据集。总共有23个完整的数据集显示良好的依从性（480%的情况下在约定给药时间的+/- 4小时内给药），3例患者在75天前停止使用，4例患者出现频繁的药物假期（>= 8天未给药），7例患者经常错过给药，依从率为
Aims and purpose To identify patterns and rates of adherence with travoprost eye drops using the Travatan dosing aid (TDA) and to present a method for graphically presenting adherence data.Methods A prospective observational cohort study of patients on travoprost (prostaglandin) monotherapy. Patients were dispensed a TDA and followed up after approximately 3 months of usage. Data were downloaded from the TDA into a computer for analysis. Analysis used inter-dose intervals (the time between each dosing) to look at adherence between days 4 and 75.Results In all, 100 patients were invited to participate, 53 agreed and complete TDA data sets were obtained from 37. In total 23 of the complete data sets showed good adherence (dosing within +/- 4 h of the agreed dosing time on 480% of occasions), 3 patients discontinued usage before 75 days, 4 showed frequent drug holidays (no dosing for >= 8 days) and 7 frequently missed doses with adherence rates of