Accumulation of dietary glycotoxins in the reproductive system of normal female rats
Accumulation of dietary glycotoxins in the reproductive system of normal female rats
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DOI：
10.1007/s00109-007-0246-6
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发表时间：
2007-12-01
影响因子：
4.7
通讯作者：
Papavassiliou, Athanasios G.
中科院分区：
文献类型：
--
作者：
Diamanti-Kandarakis, Evanthia;Piperi, Christina;Papavassiliou, Athanasios G.
本研究的目的是调查是否饮食晚期糖基化终产物（AGEs）可以在正常雌性大鼠的卵巢组织中检测到，以及它们是否可以影响其代谢或激素的配置文件。将60只正常大鼠（每组20只）随机分为高AGE（H-AGE）和低AGE（L-AGE）两组。H-AGE组大鼠空腹血糖明显高于对照组（P
The aim of the present study was to investigate whether dietary advanced glycation end-products (AGEs) can be detected in the ovarian tissue of normal female rats and whether they can affect their metabolic or hormonal profile. Sixty normal rats (20 animals in each group) were randomly assigned to regular diet, either high (H-AGE) or low (L-AGE) in AGE content for 6 months. H-AGE rats demonstrated higher levels of fasting glucose (P