Plaque Volume of Carotid Endarterectomy Specimens Measured by 3D Ultrasound Technology.
Plaque Volume of Carotid Endarterectomy Specimens Measured by 3D Ultrasound Technology.
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通过 3D 超声技术测量颈动脉内膜切除术标本的斑块体积。
DOI：
10.1016/j.jcmg.2015.10.007
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发表时间：
2016
期刊：
影响因子：
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通讯作者：
Nambi,Vijay
中科院分区：
文献类型：
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作者：
Kumar,Anirudh;Yang,EricY;Brunner,Gerd;Murray,TylerO;Virani,SalimS;Garami,Zsolt;Ballantyne,ChristieM;Morrisett,JoelD;Nambi,Vijay
与传统超声成像相比，3 维 (3D) 超声 (US) 领域的进步提高了斑块体积定量的准确性、可重复性和精确度 (1)。我们研究了一种新型 3DUS 模式量化颈动脉内膜切除术 (CEA) 后获得的动脉粥样硬化斑块体积的能力，并将其与磁共振成像 (MRI) 和真实体积 (TV) 测量的结果进行比较。这是第一项定量比较两种成像方式的离体斑块估计和真实组织学体积的研究。通过手术采集了 22 个 CEA 样本。通过体积位移评估 TV 后，使用 3.0-T MRI 系统（MAGNETOM Verio，Siemens Healthcare，埃尔兰根，德国）使用质子密度加权涡轮自旋回波序列对样本进行成像，如前所述 (2)。使用 VesselMASS 软件（莱顿大学，莱顿，荷兰）进行数据分析，该软件利用逐层平面测量法。每个 CEA 样本的质子密度加权图像上传到 LOGIQ E9 US 系统（GE Healthcare，沃瓦托萨，威斯康星州）。连接到二维美国探测器的类似 GPS 的传感器转发其位置和方向以执行配准。
Advances in the field of 3-dimensional (3D) ultrasound (US) have resulted in improved accuracy, repeatability, and precision of plaque volume quantification compared with traditional US imaging (1). We investigated the ability of a novel 3DUS modality to quantify the volume of atherosclerotic plaque obtained after carotid endarterectomy (CEA) and compared it with that measured by magnetic resonance imaging (MRI) and true volume (TV). This is the first study to quantitatively compare plaque estimation ex vivo across 2 imaging modalities and to true histological volume.Twenty-two CEA samples were surgically harvested. After TV was assessed via volume displacement, samples were imaged with a 3.0-T MRI system (MAGNETOM Verio, Siemens Healthcare, Erlangen, Germany) using a proton-density weighted turbo spin echo sequence, as described previously (2). Data analysis was performed using VesselMASS software (Leiden University, Leiden, the Netherlands) which utilized slice-by-slice planimetry. Proton-density weighted images of each CEA sample were uploaded onto a LOGIQ E9 US system (GE Healthcare, Wauwatosa, Wisconsin). A GPS-like sensor attached to the 2-dimensional US probe relayed its position and orientation to perform coregistration.